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How do we determine if a kidney cancer is at risk for spreading?

There are several factors that are used to determine the risk of an aggressive cancer:

1) Stage

  • For small kidney masses, we mostly use size to determine risk.
  • The “T” stage stands for “Tumor” and describes the risk by size.
  • Small kidney masses are in the lowest T stage, called T1a.
  • Your doctor may order a CT scan to make sure there is no cancer in other parts of the body.

2) Type of Kidney Cancer

  • One type of kidney cancer, called clear cell, is the most common among kidney cancers (70% of kidney cancers). This type causes the vast majority of metastatic disease.
  • The 2nd most common type is papillary (about 15% of kidney cancers).
  • The 3rd most common type is called chromophobe (about 5% of kidney cancers).

3) Grade of Kidney Cancer

  • A grading system can be used with either imaging tests or biopsy to predict whether a cancer will be more or less likely to spread to other parts of the body.
  • Fuhrman classification is the name of the grading system. The lowest grade is 1, and the highest grade is 4.
  • High grade cancers are most likely to spread.
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